Botox® – Vistabel® – Azzalure – Dysport® – Xeomin®
Botulinum toxin preparations – also known as Botox as a common name – are marketed under various preparations and names.
The names are:
Botox®, Vistabel®, Azzalure, Dysport® and Xeomin®.
Botox® and Vistabel® are the same toxin. The difference is that they are packed in 2 sizes under their own name.
Azzalure and Dysport® are the same toxin.
Botox / Vistabel contains:
Active substance: Botulinum toxin type A from Clostridium botulinum. Each vial contains either 50, 100 or 200 Allergan units botulinum toxin type A. Other ingredients: Human albumin (blood components) and sodium chloride (salt).
Dysport / Azzalure contains:
Active substance: Clostridium botulinum type A toxin. The other ingredients are human albumin (blood components) and lactose monohydrate (milk sugar).
Active substance: Clostridium botulinum type A neurotoxin, without complexing proteins. Other ingredients: Human albumin (blood constituents), sucrose (refined sugar).
You can find information about the ingredients on this website. Search under the different brands: https://labels.fda.gov/
No live bacteria in
All the mentioned preparations contain botulinum toxin type A, which is derived from the Clostridum botulinum bacterium.
Botulinum toxin A is the most common form of botulinum toxin.
There are no living bacteria in the botox products, only the toxin from them – and in some products: dead cells from the bacteria!
The toxin in the preparations is naturally produced under controlled conditions and contains the poison in a small (and controlled) amount.
There is little difference in the way they are made and the toxin activity (potency) varies slightly from product to product. See the chart at the bottom.
The strength of toxin in the various brands:
In 2010, an article was published examining the concentration of botulinum toxin (BoNT) in the various brands. See possibly in the link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586120/?fbclid=IwAR3KY9UgOSf6Jw4WH1OU9ZAKIu-j_DEPcNVZpPzJ9lEyp-qS43jcO6ugnV8 :
Overall, the average BoNT / A neurotoxin concentration in Botox, Dysport and Xeomin was:
Thus, in Botox, there were 0.73 nanograms of toxin in 100 units, which is equivalent to 7.3 picograms of poison in a single unit. A picogram is a trillionth of a gram.
Note! that the concentration of toxin in a unit is never constant as the material is biological and varies. In addition, a variation factor has been specified for the individual brands, and as you can see, Dysport has the largest variation factor. Ie that the strength may vary.
The figures show the average concentration!
Also note that the survey is from 2010 and that other batch numbers have been added!
Conclusion: As can be seen from the chart, Xeomin contains the highest neurotoxin activity, as there is the least picogram of poison per day. unit. Then comes Dysport and eventually Botox.