Poison’s effect on nerves and muscles:
The toxin is absorbed into the nervous system – or more specifically, the nerve ends. From there, the poison paralyzes the nerve cell.
The nerves control the muscles. When the nerve cells are paralyzed, the muscles no longer receive signals from the nervous system and thus become paralyzed..
There is a link to 3 illustrations here:
As you can see from illustration # 1 in the link, the botox penetrates a nerve end and creates a “ring” / block around a substance called acetylcholine. Acetylcholine is an organic chemical that works in the brain and body of many types of animals and humans, like a neurotransmitter (neuro = nerve and transmitter = send a message). – It is a chemical message released by nerve cells to send signals to other cells, such as neurons, muscle cells and gland cells. In other words, acetylcholine is the chemical that motor neurons in the nervous system release to activate muscles.
Since botox blocks the drug, it is said that botox works muscle relaxant, but drugs that affect the nervous system can also have very dangerous effects, from paralysis to cramps.
In addition to this, botox also goes in and closes the snap 25 protein. The Snap 25 protein is a membrane-bound protein that is anchored to the membranes of the nerve cells. If you see the illustration at the bottom of the link, you see the membranes being cut off by the botulinum toxin, so that the transport particles from the nerve endings cannot fuse with the nerve membrane.
The last illustration shows that the muscle expands as communication with the nerve cells ceases. – The nerve endings then make safety nerve threads (sprouts), which later retreat and perish. – In other words, the nerve endings are completely or partially destroyed by botulinum toxin and the communication between nerves and muscles is only restored again as new nerve fibers grow.
See possibly another illustration here (page 618): https://books.google.dk/books?id=kIJXDwAAQBAJ&pg=PA618&lpg=PA618&dq=The+endplate+expands+and+collateral+axonal+sprouts+emerge.+Sprouts+subsequently+retract.&source=bl&ots=cNAB6yw0jC&sig=ACfU3U2_hBeWVWTTPBELb2xMZymm22_QyQ&hl=da&sa=X&ved=2ahUKEwjHq4aAj6vmAhUE4aQKHRnxDC8Q6AEwAHoECAoQAQ#v=onepage&q=The%20endplate%20expands%20and%20collateral%20axonal%20sprouts%20emerge.%20Sprouts%20subsequently%20retract.&f=false